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    Dear Colleagues:<br>
    <br>
    Thank those who have given inputs.  Indeed, the Manifesto does not
    need to be linked with any society.  Therefore the last paragraph
    about the new society has been removed.   In addition, some
    citations have been removed and some brain evidence added.  The
    removal of the last paragraph is a major change.<br>
    <br>
    ----<br>
    The Brain Principles Manifesto<br>
    (Draft Version 4.0)<br>
    <br>
    Feb. 27, 2015<br>
    <br>
    <meta name="Title" content="">
    <p class="MsoNormal">Historically, public acceptance of science was
      slow.<span style="mso-spacerun:yes">  </span>For example, Charles
      Darwin waited about 20
      years (from the <span style="mso-fareast-font-family:"Times
        New Roman"">1830s
        to 1858)</span> to publish his theory of evolution for fear of
      public
      reaction.<span style="mso-spacerun:yes">  </span>About 20 years
      later (by the
      1870s) the scientific community and much of the general public had
      accepted
      evolution as a fact. <span style="mso-spacerun:yes">  </span>Of
      course, the
      debate on evolution still goes on today. <o:p></o:p></p>
    <p class="MsoNormal"><o:p> </o:p></p>
    <p class="MsoNormal">Is the public acceptance of science<span
        style="font-family:
        华文黑体;mso-bidi-font-family:华文黑体;mso-fareast-language:ZH-CN"> </span>faster
      in
      modern days?<span style="mso-spacerun:yes">  </span>Not
      necessarily so, even
      though we have now better and faster means to communicate.<span
        style="mso-spacerun:yes">  </span><span
        style="mso-spacerun:yes"> </span>The primary
      reason is still the same but much more severe<span class="st"><span
          style="mso-fareast-font-family:"Times New Roman"">—</span></span>the
      remaining
      open scientific problems are more complex and the required
      knowledge to convincingly
      understand goes beyond a typical single person. <o:p></o:p></p>
    <p class="MsoNormal"><o:p> </o:p></p>
    <p class="MsoNormal">For instance, network-like brain computation <span
        class="st"><span style="mso-fareast-font-family:"Times New
          Roman"">— </span></span>connectionist
      computation <span class="st"><span
          style="mso-fareast-font-family:"Times New Roman"">—
        </span></span>has been long doubted and ignored by industry.<span
        style="mso-spacerun:yes">   </span><i
        style="mso-bidi-font-style:normal">Convolutional
        deep</i> networks appeared by at least 1980.<span
        style="mso-spacerun:yes"> 
      </span><i style="mso-bidi-font-style:normal">Max-pooling</i> in
      deep and fully
      automatic learning networks was published by 1992.<span
        style="mso-spacerun:yes">  </span>However, Apple, Baidu,
      Google, Microsoft,
      Samsung, and other major related companies did not show
      considerable interest
      till after 2012.<span style="mso-spacerun:yes">  </span>That is a
      delay of
      about 20 years.<span style="mso-spacerun:yes">  </span>The two
      techniques above
      are not very difficult to understand. <span
        style="mso-spacerun:yes"> </span>However, these two suddenly hot
      techniques have
      already been proved obsolete by the discoveries of more
      fundamental and
      effective principles of the brain, six of which are intuitively
      explained below.<span style="mso-spacerun:yes">  </span><span
        style="mso-spacerun:yes"> </span><o:p></o:p></p>
    <p class="MsoNormal"><o:p> </o:p></p>
    <p class="MsoNormal">Industrial and academic interests have been
      keen on a
      combination of two things <span class="st"><span
          style="mso-fareast-font-family:
          "Times New Roman"">—</span></span> easily
      understandable tests and major
      companies are involved.<span style="mso-spacerun:yes">  </span>However,
      the newly
      known brain principles have told us that the ways to conduct such
      tests will give
      only vanishing gains that do not lead to a human-like zero error
      rate,
      regardless how many more images can be added to the training sets
      and how long
      the Moore’s Law can continue. <span style="mso-spacerun:yes"> </span>Why?<span
        style="mso-spacerun:yes">  </span>This is because all these
      static training
      sets prevent participants from considering autonomous object
      segmentation.<span style="mso-spacerun:yes">  </span>The neurons
      in human babies learn to segment
      objects through baby’s interaction with the real physical world.<span
        style="mso-spacerun:yes">  </span>Do our industry and public
      need another 20
      years?<span style="mso-spacerun:yes">  </span>Or more? <o:p></o:p></p>
    <p class="MsoNormal"><o:p> </o:p></p>
    <p class="MsoNormal">October 2011<span
        style="font-family:华文黑体;mso-bidi-font-family:
        华文黑体;mso-fareast-language:ZH-CN"> </span>a highly respected
      multi-<span style="font-family:Times">disciplinary</span>
      professor kindly wrote: “I tell
      these students that they can work on brains and do good science,
      or work on
      robots and do good engineering.<span style="mso-spacerun:yes">  </span>But
      if
      they try to do both at once, the result will be neither good
      science nor good engineering.”<span style="mso-spacerun:yes">  </span>How
      long does it take for the industry and
      public to accept that the pessimistic<span
        style="font-family:Times;mso-bidi-font-family:
        华文黑体;mso-fareast-language:ZH-CN"> view</span> of the brain was
      no longer true
      even then?<o:p></o:p></p>
    <p class="MsoNormal"><o:p> </o:p></p>
    <p class="MsoNormal">The brain principles that have already <span
        style="font-family:Times;mso-bidi-font-family:华文黑体;mso-fareast-
        language:ZH-CN">been
      </span>discovered could bring fundamental changes in the way
      humans live, the
      way countries and societies are organized, our industry, our
      economy, and the
      way humans treat one another.<span style="mso-spacerun:yes">  </span><span
        style="font-family:华文黑体;mso-bidi-font-family:华文黑体;mso-fareast-
        language:ZH-CN"><o:p></o:p></span></p>
    <p class="MsoNormal"><o:p> </o:p></p>
    <p class="MsoNormal">The known brain principles have told us that
      the brain of
      anybody, regardless of his education and experience, is
      fundamentally shortsighted,
      in both space and time.<span style="mso-spacerun:yes">  </span>Prof.
      <span class="st"><span style="mso-fareast-font-family:"Times
          New Roman"">Jonathan Haidt
          documented well such shortsightedness in his book “</span></span><a
href="http://www.amazon.com/The-Righteous-Mind-Politics-Religion/dp/0307455777"><i
          style="mso-bidi-font-style:normal"><span
            style="mso-fareast-font-family:"Times New Roman"">The
Righteous
            Mind: Why Good People Are Divided by Politics and Religion</span></i></a><span
        class="st"><span style="mso-fareast-font-family:"Times New
          Roman"">”, although not
          in terms of brain computation. <span style="mso-spacerun:yes"> </span><o:p></o:p></span></span></p>
    <p class="MsoNormal"><span class="st"><span
          style="mso-fareast-font-family:"Times New Roman""><o:p> </o:p></span></span></p>
    <p class="MsoNormal"><span class="st"><span
          style="mso-fareast-font-family:"Times New Roman"">In
          terms of brain computation, the circuits in your brain
          self-wire </span></span><span
        style="mso-fareast-font-family:"Times New Roman"">beautifully<span
          class="st"> and
          precisely according to your real-time experience (the genome
          only regulates)
          and their various invariance properties required for
          abstraction also largely
          depend on experience.<span style="mso-spacerun:yes">  </span>Serotonin
          (caused
          by, e.g., threats), dopamine (caused by e.g., praise), and
          other neural
          transmitters quickly change the way these circuits work so
          that neurons for more
          long-term thoughts lost in competition to fire.<span
            style="mso-spacerun:yes"> 
          </span>Therefore, you make long-term mistakes but you still
          feel you are right
          (e.g., indignant and patriotic). <span
            style="mso-spacerun:yes">  </span>Everybody is like that,
          including every
          politician.<span style="mso-spacerun:yes">  </span>Depending
          on experience, shortsightedness
          varies in terms of subject matter. <span
            style="mso-spacerun:yes"> </span><o:p></o:p></span></span></p>
    <p class="MsoNormal"><span class="st"><span
          style="mso-fareast-font-family:"Times New Roman""><o:p> </o:p></span></span></p>
    <p class="MsoNormal"><span class="st"><span
          style="mso-fareast-font-family:"Times New Roman"">Surprisingly,
to
          understand how the brain works requires a sophisticated
          automata theory in
          computer science. See J. Weng, </span></span><a
href="http://www.google.com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=1&ved=0CCAQFjAA&url=http%3A%2F%2Fwww.scirp.org%2Fjournal%2FPaperDownload.aspx%3FpaperID%3D53728&ei=21rnVP7fB4KZyAT-noH4Cg&usg=AFQjCNEzHz-YDhivI1esDtgKg84SEx4RuQ&bvm=bv.86475890,d.aWw&cad"><i
          style="mso-bidi-font-style:normal"><span
            style="mso-fareast-font-family:"Times New Roman"">Brain
          </span></i><i style="mso-bidi-font-style:normal"><span
            style="font-family:Times;
            mso-bidi-font-family:华文黑体">as</span></i><i
          style="mso-bidi-font-style:normal"><span
            style="mso-fareast-font-family:"Times New Roman"">
            an Emergent Finite
            Automaton: A Theory and Three Theorems</span></i></a><span
        class="st"><span style="mso-fareast-font-family:"Times New
          Roman"">, <i style="mso-bidi-font-style:
            normal">IJIS</i>, 2015, which proposed the following six
          brain principles:<o:p></o:p></span></span></p>
    <p class="MsoListParagraphCxSpFirst"
      style="margin-left:42.0pt;mso-add-space:
      auto;text-indent:-.25in;mso-list:l0 level1 lfo1"><!--[if !supportLists]--><span
        class="st"><span style="mso-fareast-font-family:"Times New
          Roman""><span style="mso-list:Ignore">1.<span
              style="font:7.0pt "Times New Roman"">    
            </span></span></span></span><!--[endif]--><span class="st"><span
          style="mso-fareast-font-family:
          "Times New Roman"">The developmental program
          (genome-like, task-nonspecific)
          regulates the development (i.e., lifetime learning) of a
          task-nonspecific
          “brain” network (DN).<span style="mso-spacerun:yes">  </span>The
          DN is of
          general-purpose—can learn any body-capable tasks, in
          principle. <o:p></o:p></span></span></p>
    <p class="MsoListParagraphCxSpMiddle"
      style="margin-left:42.0pt;mso-add-space:
      auto;text-indent:-.25in;mso-list:l0 level1 lfo1"><!--[if !supportLists]--><span
        class="st"><span style="mso-fareast-font-family:"Times New
          Roman""><span style="mso-list:Ignore">2.<span
              style="font:7.0pt "Times New Roman"">    
            </span></span></span></span><!--[endif]--><span class="st"><span
          style="mso-fareast-font-family:
          "Times New Roman"">The brain’s images are naturally
          sensed images of cluttered
          scenes where many objects mix.<span style="mso-spacerun:yes"> 
          </span>As a
          child learns to see, teachers do not draw a bounding box
          around each learned object
          in her retinal image — DN self-learns segmentation.<o:p></o:p></span></span></p>
    <p class="MsoListParagraphCxSpMiddle"
      style="margin-left:42.0pt;mso-add-space:
      auto;text-indent:-.25in;mso-list:l0 level1 lfo1"><!--[if !supportLists]--><span
        class="st"><span style="mso-fareast-font-family:"Times New
          Roman""><span style="mso-list:Ignore">3.<span
              style="font:7.0pt "Times New Roman"">    
            </span></span></span></span><!--[endif]--><span class="st"><span
          style="mso-fareast-font-family:
          "Times New Roman"">The brain’s muscles have multiple
          subareas where each
          subarea represents either declarative knowledge (e.g.,
          abstract concepts such
          as location, type, scale, etc.) or non-declarative knowledge
          (e.g., driving a
          car or riding a bicycle). <o:p></o:p></span></span></p>
    <p class="MsoListParagraphCxSpMiddle"
      style="margin-left:42.0pt;mso-add-space:
      auto;text-indent:-.25in;mso-list:l0 level1 lfo1"><!--[if !supportLists]--><span
        class="st"><span style="mso-fareast-font-family:"Times New
          Roman""><span style="mso-list:Ignore">4.<span
              style="font:7.0pt "Times New Roman"">    
            </span></span></span></span><!--[endif]--><span class="st"><span
          style="mso-fareast-font-family:
          "Times New Roman"">Every area in the “brain” DN
          emerges (does not statically exist,
          see M. Sur et al. <i style="mso-bidi-font-style:normal">Nature</i>
          2000 and P.
          Voss, <i style="mso-bidi-font-style:normal">Frontiers in
            Psychology</i> 2013) using
          a unified area function whose feature development is nonlinear
          but free of
          local minima, contrary to engineering intuition.<o:p></o:p></span></span></p>
    <p class="MsoListParagraphCxSpMiddle"
      style="margin-left:42.0pt;mso-add-space:
      auto;text-indent:-.25in;mso-list:l0 level1 lfo1"><!--[if !supportLists]--><span
        class="st"><span style="mso-fareast-font-family:"Times New
          Roman""><span style="mso-list:Ignore">5.<span
              style="font:7.0pt "Times New Roman"">    
            </span></span></span></span><!--[endif]--><span class="st"><span
          style="mso-fareast-font-family:
          "Times New Roman"">The “brain” DN learns
          incrementally—taking one-pair of
          sensory pattern and motor pattern at a time to update the
          “brain” and
          discarding the pair immediately after. <span
            style="mso-spacerun:yes"> </span>Namely,
          a real brain has only one pair of stereoscopic retinas. <o:p></o:p></span></span></p>
    <p class="MsoListParagraphCxSpLast"
      style="margin-left:42.0pt;mso-add-space:auto;
      text-indent:-.25in;mso-list:l0 level1 lfo1"><!--[if !supportLists]--><span
        class="st"><span style="mso-fareast-font-family:"Times New
          Roman""><span style="mso-list:Ignore">6.<span
              style="font:7.0pt "Times New Roman"">    
            </span></span></span></span><!--[endif]--><span class="st"><span
          style="mso-fareast-font-family:
          "Times New Roman"">The “brain” DN is always
          optimal—Each DN update in real time
          computes the maximum likelihood estimate of the “brain”,
          conditioned on the
          limited computational resources and the limited learning
          experience in its
          “life” so far.<o:p></o:p></span></span></p>
    <p class="MsoNormal" style="margin-left:24.0pt"><span class="st"><span
          style="mso-fareast-font-family:"Times New Roman""><o:p> </o:p></span></span></p>
    <p class="MsoNormal"><span class="st"><span
          style="mso-fareast-font-family:"Times New Roman"">The
logic
          completeness of a brain is (partially, not all) understood by
          a universal
          Turing Machine in DN which is like our modern-day computer, in
          principle.<span style="mso-spacerun:yes">  </span>This
          automaton brain model proposes that each
          brain is an automaton, but also very different from all
          traditional symbolic
          automata because it programs itself—emergent.<span
            style="mso-spacerun:yes"> 
          </span>No traditional automata can program themselves in the
          sense of Turing
          Machine but a brain automaton does. <o:p></o:p></span></span></p>
    <p class="MsoNormal"><span class="st"><span
          style="mso-fareast-font-family:"Times New Roman""><o:p> </o:p></span></span></p>
    <p class="MsoNormal"><span class="st"><span
          style="mso-fareast-font-family:"Times New Roman"">The
automaton
          brain model has predicted that neural circuits dynamically and
          precisely
          record the statistics of experience, roughly consistent with
          neural anatomy
          (e.g., Felleman & Van Essen, <i
            style="mso-bidi-font-style:normal">Cerebral
            Cortex</i>, 1991). <span style="mso-spacerun:yes"> </span>In
          particular, the
          model predicted that “shifting attention between `humans’ and
          `vehicles’
          dramatically changes brain representation of all categories”
          (J. Gallant et al.
          <i style="mso-bidi-font-style:normal">Nature Neuroscience</i>,
          2013) and that human
          attention “can regulate the activity of their neurons in the
          medial temporal
          lobe” (C. Koch et al. <i style="mso-bidi-font-style:normal">Nature</i>,
          2010). <span style="mso-spacerun:yes"> </span>The “place”
          cells work of the 2014 Nobel Prize
          in Physiology or Medicine implies that neurons encode
          exclusively bottom-up
          information (place). The automaton brain model challenges such
          a view: Neurons
          represent a combination of both bottom-up (e.g., place) and
          top-down context (e.g.,
          goal) as reported by Koch et al. and Gallant et al. <o:p></o:p></span></span></p>
    <p class="MsoNormal"><span class="st"><span
          style="mso-fareast-font-family:"Times New Roman""><o:p> </o:p></span></span></p>
    <p class="MsoNormal"><span class="st"><span
          style="mso-fareast-font-family:"Times New Roman"">Unfortunately,
the
          automaton brain model implies that all neuroscientists and
          neural network
          researchers are unable to understand the brain of their
          studies without a rigorous
          training in automata theory. <span style="mso-spacerun:yes">  </span>For
example,
          traditional models for nervous systems and neural networks
          focus on
          pattern recognition and do not have the capabilities of a
          grounded symbol
          system (e.g., “rulefully combining and recombining,” Stevan
          Harnad, <i style="mso-bidi-font-style:normal">Physica D,</i>
          1990).<span style="mso-spacerun:yes">  </span>The automata
          theory deals with such
          capabilities. <span style="mso-spacerun:yes"> </span>Does
          this new knowledge
          stun our students and researchers or guide them so their time
          is better spent?<o:p></o:p></span></span></p>
    <p class="MsoNormal"><span class="st"><span
          style="mso-fareast-font-family:"Times New Roman""><o:p> </o:p></span></span></p>
    <p class="MsoNormal"><span class="st"><span
          style="mso-fareast-font-family:"Times New Roman"">Understanding
brain
          automata would enable us to see answers to a wide variety of
          important
          questions, some of which are raised below. <span
            style="mso-spacerun:yes"> </span>We do not provide yes/no
          answers here, only
          raise questions.<span style="mso-spacerun:yes">  </span>The
          automaton brain
          model predicts that there is no absolute right or wrong in any
          brain but its
          environmental experiences wire and rewire the brain. <o:p></o:p></span></span></p>
    <p class="MsoNormal"><span class="st"><span
          style="mso-fareast-font-family:"Times New Roman""><o:p> </o:p></span></span></p>
    <p class="MsoNormal"><span class="st"><span
          style="mso-fareast-font-family:"Times New Roman"">In
          each question of social science, we may have two sides, Side A
          with more
          knowledge due to the relatively more open political and
          ideological environment
          and Side B with less knowledge due to relatively less open
          political and ideological
          environment, but all having normal human brains that deserve
          respect.<span style="mso-spacerun:yes">   </span>Is it more
          scientifically productive for
          Side A to make friends with Side B so that Side B is not
          threatened and resist?<span style="mso-spacerun:yes">   </span>Side
          A wants the brains in Side B to rewire
          for good instead of for bad, doesn’t it?<o:p></o:p></span></span></p>
    <p class="MsoNormal"><span class="st"><span
          style="mso-fareast-font-family:"Times New Roman""><o:p> </o:p></span></span></p>
    <p class="MsoNormal"><span class="st"><span
          style="mso-fareast-font-family:"Times New Roman"">How
can
          our industry and public understand that the door for
          understanding brains has
          opened for them?<span style="mso-spacerun:yes">  </span>How
          can they see the
          economical outlooks that this opportunity leads them to?<o:p></o:p></span></span></p>
    <p class="MsoNormal"><span class="st"><span
          style="mso-fareast-font-family:"Times New Roman""><o:p> </o:p></span></span></p>
    <p class="MsoNormal"><span class="st"><span
          style="mso-fareast-font-family:"Times New Roman"">How
should
          our educational system reform to prepare our many bright minds
          for the
          new brain age?<span style="mso-spacerun:yes">   </span>Has
          our government been
          prompt to properly respond to this modern call from the
          nature?</span></span><span class="st"><span
          style="font-family:华文黑体;mso-bidi-font-family:华文黑体;mso-fareast-language:
          ZH-CN"><o:p></o:p></span></span></p>
    <p class="MsoNormal"><span class="st"><span
          style="mso-fareast-font-family:"Times New Roman""><o:p> </o:p></span></span></p>
    <p class="MsoNormal"><span class="st"><span
          style="mso-fareast-font-family:"Times New Roman"">How
should
          our young generation</span></span><span class="st"><span
          style="font-family:
          华文黑体;mso-bidi-font-family:华文黑体;mso-fareast-language:ZH-CN"> </span></span><span
        class="st"><span style="mso-fareast-font-family:"Times New
          Roman"">act for the
          new opportunity that is unfolding before their eyes?<span
            style="mso-spacerun:yes">  </span>Is a currently narrowly
          defined academic degree
          sufficient for their career?<o:p></o:p></span></span></p>
    <p class="MsoNormal"><o:p> </o:p></p>
    <p class="MsoNormal">How can everybody take advantage of the new
      knowledge about
      his own brain so that he is more successful in his career?<span
        style="mso-spacerun:yes">  </span><o:p></o:p></p>
    ---<br>
    Please continue to send your comments. <br>
    <br>
    -John
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<![endif]--><!--StartFragment--><!--EndFragment--><br>
    <pre class="moz-signature" cols="72">-- 
--
Juyang (John) Weng, Professor
Department of Computer Science and Engineering
MSU Cognitive Science Program and MSU Neuroscience Program
428 S Shaw Ln Rm 3115
Michigan State University
East Lansing, MI 48824 USA
Tel: 517-353-4388
Fax: 517-432-1061
Email: <a class="moz-txt-link-abbreviated" href="mailto:weng@cse.msu.edu">weng@cse.msu.edu</a>
URL: <a class="moz-txt-link-freetext" href="http://www.cse.msu.edu/~weng/">http://www.cse.msu.edu/~weng/</a>
----------------------------------------------

</pre>
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